The economic burden of systemic sclerosis related pulmonary arterial hypertension in Australia
نویسندگان
چکیده
منابع مشابه
Pulmonary arterial hypertension in systemic sclerosis.
Pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc) is a complex clinical situation resulting from restricted flow through the pulmonary arterial circulation ending in increased pulmonary vascular resistance and right heart failure. PAH is a common and life-threatening complication in connective tissue diseases, specifically in SSc if not treated rapidly and adequately. Based on t...
متن کاملThe heart and pulmonary arterial hypertension in systemic sclerosis.
Systemic sclerosis (SSc) is an autoimmune connective tissue disease characterized by vasculopathy and progressive fibrosis of the skin and visceral organs (gastrointestinal tract, heart, kidneys and lungs). Although the prevalence is low, SSc is a disease with high morbidity and mortality. Since pulmonary arterial hypertension (PAH) associated with SSc (SSc-PAH) and clinically evident cardiac i...
متن کاملDeterminants of exercise-induced pulmonary arterial hypertension in systemic sclerosis.
BACKGROUND Exercise-induced pulmonary arterial hypertension (EIPH) in systemic sclerosis (SSc) has already been observed but its determinants remain unclear. The aim of this study was to determine the incidence and the determinants of EIPH in SSc. METHODS AND RESULTS We prospectively enrolled 63 patients with SSc (age 54±3years, 76% female) followed in CHU Sart-Tilman in Liège. All patients u...
متن کاملTherapy of pulmonary arterial hypertension in systemic sclerosis: an update.
Pulmonary arterial hypertension (PAH) affects 10% to 15% of patients with systemic sclerosis and is a major cause for disease-related morbidity and mortality. Over the past decade, significant progress has been made in the understanding of the pathophysiologic mechanisms underlying PAH. This progress led to the development of several new treatment options and, as a result, dramatically improved...
متن کاملSerum VEGF levels are related to the presence of pulmonary arterial hypertension in systemic sclerosis
BACKGROUND The association between systemic sclerosis and pulmonary arterial hypertension (PAH) is well recognized. Vascular endothelial growth factor (VEGF) has been reported to play an important role in pulmonary hypertension. The aim of the present study was to examine the relationship between systolic pulmonary artery pressure, clinical and functional manifestations of the disease and serum...
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ژورنال
عنوان ژورنال: BMC Pulmonary Medicine
سال: 2019
ISSN: 1471-2466
DOI: 10.1186/s12890-019-0989-1